diff --git a/sdk/cmake/gcc.cmake b/sdk/cmake/gcc.cmake
index 5a37db32dea..bc72c977773 100644
--- a/sdk/cmake/gcc.cmake
+++ b/sdk/cmake/gcc.cmake
@@ -160,6 +160,7 @@ endif()
 
 # Other
 if(ARCH STREQUAL "amd64")
+    add_compile_options(-mcx16) # Generate CMPXCHG16
     add_definitions(-U_X86_ -UWIN32)
 elseif(ARCH STREQUAL "arm")
     add_definitions(-U_UNICODE -UUNICODE)
diff --git a/sdk/cmake/msvc.cmake b/sdk/cmake/msvc.cmake
index ede1597a454..e19e8e8b6ff 100644
--- a/sdk/cmake/msvc.cmake
+++ b/sdk/cmake/msvc.cmake
@@ -41,6 +41,9 @@ endif()
 add_compile_options(/GS-)
 
 if(CMAKE_C_COMPILER_ID STREQUAL "Clang")
+    if(ARCH STREQUAL "amd64")
+        add_compile_options(-mcx16) # Generate CMPXCHG16B
+    endif()
     set(CMAKE_CL_SHOWINCLUDES_PREFIX "Note: including file: ")
 endif()
 
diff --git a/sdk/include/crt/mingw32/intrin_x86.h b/sdk/include/crt/mingw32/intrin_x86.h
index 1bfae865d77..fa6a74f6407 100644
--- a/sdk/include/crt/mingw32/intrin_x86.h
+++ b/sdk/include/crt/mingw32/intrin_x86.h
@@ -699,6 +699,14 @@ __INTRIN_INLINE long long _InterlockedCompareExchange64(volatile long long * Des
 #endif /* (__GNUC__ * 10000 + __GNUC_MINOR__ * 100 + __GNUC_PATCHLEVEL__) > 40100 && defined(__x86_64__) */
 #endif /* !HAS_BUILTIN(_InterlockedCompareExchange64) */
 
+#if defined(__x86_64__) && !HAS_BUILTIN(_InterlockedCompareExchange128)
+__INTRIN_INLINE unsigned char _InterlockedCompareExchange128(_Interlocked_operand_ __int64 volatile* Destination, __int64 ExchangeHigh, __int64 ExchangeLow, __int64* ComparandResult)
+{
+    __int64 xchg[2] = { ExchangeLow, ExchangeHigh };
+    return __sync_bool_compare_and_swap((__uint128_t*)Destination, *((__uint128_t*)ComparandResult), *((__uint128_t*)xchg));
+}
+#endif
+
 #ifdef __i386__
 __INTRIN_INLINE long _InterlockedAddLargeStatistic(volatile long long * Addend, long Value)
 {